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PAPPA2 Antibody - N-terminal region : FITC (ARP42555_P050-FITC)

Selected Variant

ARP42555_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Pappalysin 2

Gene Aliases

PAPPE, PLAC3, PAPP-E, PAPP-A2

Gene ID

60676

Swiss Prot

A9Z1Y8

Accession Number

NP_068755

Host

Rabbit

Reactivity

Human, Rat, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PAPPA2

Target

PAPPA2 is a metalloproteinase which specifically cleaves IGFBP-5. It shows limited proteolysis toward IGFBP-3.

Partner Proteins

ZNF512B; SMAD4; ATF7IP; IGFBP5; IGFBP3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PAPPA2 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Guinea Pig: 85%; Human: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

References & Citations

Gregory, S.G., (2006) Nature 441 (7091), 315-321

Shipping Conditions

Wet Ice

Protein Length

827

NCBI Gene Symbol

PAPPA2

NCBI GB Accession Number

PAPPA2

Host or Source

Rabbit

Protein Name

Pappalysin-2

Nucleotide Accession Number

NM_021936

Peptide Sequence

PPDLTENPAGLRGAVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESL

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