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DOK5 Antibody - N-terminal region : HRP (ARP42518_P050-HRP)

Product Specifications

Gene Name

Docking protein 5

Gene Aliases

IRS6, IRS-6, C20orf180

Gene ID

55816

Swiss Prot

Q9P104

Accession Number

NP_060901

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DOK5

Target

DOK5 is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. It interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.

Partner Proteins

EGFR; CCDC85B; BNIP3L; NTRK2; NTRK3; RET; INSR; IGF1R

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Shi, L., (2006) Cell. Signal. 18 (11), 1995-2003

Shipping Conditions

Wet Ice

Product Datasheet

Anti-DOK5 (ARP42518_P050-HRP) antibody

Protein Length

306

NCBI Gene Symbol

DOK5

NCBI GB Accession Number

DOK5

Host or Source

Rabbit

Protein Name

Docking protein 5

Nucleotide Accession Number

NM_018431

Peptide Sequence

GPKRLEKFSDERAAYFRCYHKVTELNNVKNVARLPKSTKKHAIGIYFNDD

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