Esrp2 Antibody - C-terminal region : FITC (ARP42490_P050-FITC)
Selected Variant
ARP42490_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Epithelial splicing regulatory protein 2
Gene Aliases
Rbm35, Rbm35b, 9530027K23Rik
Gene ID
77411
Swiss Prot
Q8K0G8
Accession Number
NP_789808
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide corresponding to a region of Mouse
Target
Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT) . It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
77kDa
Shipping Conditions
Wet Ice
Protein Length
717
NCBI Gene Symbol
ESRP2
NCBI GB Accession Number
Esrp2
Host or Source
Rabbit
Protein Name
Epithelial splicing regulatory protein 2
Nucleotide Accession Number
NM_176838
Peptide Sequence
LLPAARVPAAATPLAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPPT
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