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GTSE1 Antibody - N-terminal region : FITC (ARP42470_P050-FITC)

Selected Variant

ARP42470_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

G-2 and S-phase expressed 1

Gene Aliases

B99

Gene ID

51512

Swiss Prot

Q9NYZ3

Accession Number

NP_057510

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GTSE1

Target

GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

Partner Proteins

UBC; HNRNPD; BARD1; SH3KBP1; SUMO2; USP11

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

GTSE1 is strongly supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

76kDa

References & Citations

Beausoleil, S.A., (2006) Nat. Biotechnol. 24 (10), 1285-1292

Shipping Conditions

Wet Ice

Protein Length

720

NCBI Gene Symbol

GTSE1

NCBI GB Accession Number

GTSE1

Host or Source

Rabbit

Protein Name

G2 and S phase-expressed protein 1

Nucleotide Accession Number

NM_016426

Peptide Sequence

NNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAA

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