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NECTIN3 Antibody - N-terminal region: Biotin (ARP42446_P050-Biotin)

Product Specifications

Gene Name

Nectin cell adhesion molecule 3

Gene Aliases

PPR3, PRR3, CD113, PVRL3, PVRR3, CDW113, NECTIN-3

Gene ID

25945

Swiss Prot

Q9NQS3

Accession Number

NP_056295

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PVRL3

Target

This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

Partner Proteins

NOTCH2NL; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; KRTAP4-2; RGS20; UBC; BAG3; TIGIT; PVRL2; PVRL1; PARD3; PVR; MLLT4; PVRL3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

Shipping Conditions

Wet Ice

Protein Length

549

NCBI Gene Symbol

NECTIN3

Protein Name

Nectin-3

Nucleotide Accession Number

NM_015480

Curated Selection

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