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NECTIN3 Antibody - N-terminal region : Biotin (ARP42446_P050-Biotin)

Product Specifications

Gene Name

Nectin cell adhesion molecule 3

Gene Aliases

PPR3, PRR3, CD113, PVRL3, PVRR3, CDW113, NECTIN-3

Gene ID

25945

Swiss Prot

Q9NQS3

Accession Number

NP_056295

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PVRL3

Target

This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

Partner Proteins

NOTCH2NL; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; KRTAP4-2; RGS20; UBC; BAG3; TIGIT; PVRL2; PVRL1; PARD3; PVR; MLLT4; PVRL3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Fujito, T., (2005) J. Cell Biol. 171 (1), 165-173

Shipping Conditions

Wet Ice

Protein Length

549

NCBI Gene Symbol

NECTIN3

NCBI GB Accession Number

NECTIN3

Host or Source

Rabbit

Protein Name

Nectin-3

Nucleotide Accession Number

NM_015480

Peptide Sequence

SGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAI

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