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ATP6V0A2 Antibody - N-terminal region : Biotin (ARP42365_P050-Biotin)

Selected Variant

ARP42365_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

ATPase, H+ transporting, lysosomal V0 subunit a2

Gene Aliases

A2, RTF, TJ6, WSS, a2V, ARCL, J6B7, STV1, TJ6M, TJ6S, VPH1, ARCL2A, ATP6A2, ATP6N1D

Gene ID

23545

Swiss Prot

Q9Y487

Accession Number

NP_036595

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V0A2

Target

The multisubunit vacuolar-type proton pump (H (+) -ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes, lysosomes, clathrin-coated vesicles, secretory vesicles, and chromaffin granules, and it is found at high density in the plasma membrane of certain specialized cells. H (+) -ATPases are comprised of a peripheral V (1) domain and an integral membrane V (0) domain; ATP6V0A2 is a component of the V (0) domain.The multisubunit vacuolar-type proton pump (H (+) -ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes, lysosomes, clathrin-coated vesicles, secretory vesicles, and chromaffin granules, and it is found at high density in the plasma membrane of certain specialized cells. H (+) -ATPases are comprised of a peripheral V (1) domain and an integral membrane V (0) domain; ATP6V0A2 is a component of the V (0) domain (Smith et al., 2003 [PubMed 14580332]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; RPL10L; PTRH2; ATP6V1D; RPS15; RPS2; SLC25A3; AKT1; ELAVL1; CYTH2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 83%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 92%; Rat: 100%; Yeast: 79%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

98kDa

References & Citations

Kornak, U., (2008) Nat. Genet. 40 (1), 32-34

Shipping Conditions

Wet Ice

Protein Length

856

NCBI Gene Symbol

ATP6V0A2

NCBI GB Accession Number

ATP6V0A2

Host or Source

Rabbit

Protein Name

V-type proton ATPase 116 kDa subunit a isoform 2

Nucleotide Accession Number

NM_012463

Peptide Sequence

INRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRKN

Subunit

A isoform 2

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