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FST Antibody - middle region : Biotin (ARP42286_P050-Biotin)

Product Specifications

Gene Name

Follistatin

Gene Aliases

FS

Gene ID

10468

Swiss Prot

B5BU94

Accession Number

NP_006341

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human FST

Target

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.

Partner Proteins

INHBA; BMPR2; BMPR1A; C8orf33; TK1; MEST; INHBE; INHA; FN1; BMP5; TXN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Goat: 92%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

References & Citations

Eichberger, T., (2008) J. Biol. Chem. 283 (18), 12426-12437

Shipping Conditions

Wet Ice

Protein Length

317

NCBI Gene Symbol

FST

NCBI GB Accession Number

FST

Host or Source

Rabbit

Protein Name

Follistatin

Nucleotide Accession Number

NM_006350

Peptide Sequence

ALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCN

Frequently Asked Questions

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