KRT1 Antibody - middle region : Biotin (ARP42278_P050-Biotin)

KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

MDM2; LGR4; EED; ESR1; ADRB2; PAN2; Iqcb1; Nphp4; Cep290; Nphp1; Invs; GRDX; VCAM1; UBC; ITGA4; FN1; CDH1; APOA1; ALB; MAGOH; EIF4A3; KRT10; KRT9; KRT2; SLC25A5; SHC1; PIK3R2; INPPL1; GRB2; EPS15; CRK; AP2M1; CBL; UBASH3B; NEDD8; CAND1; DCUN1D1; COPS5; CO

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.