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MSLN Antibody - middle region : FITC (ARP42262_P050-FITC)

Product Specifications

Gene Name

Mesothelin

Gene Aliases

MPF, SMRP

Gene ID

10232

Swiss Prot

Q13421-3

Accession Number

NP_005814

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MSLN

Target

An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin.An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants.

Partner Proteins

RSG1; MRPL1; RNMTL1; MRPL16; ZBTB43; MRPL28; LAMTOR3; RALA; NDUFB9; NDUFB5; MPV17; ATP6V1A; MUC16

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

References & Citations

Johnson, M.D., (2008) J. Histochem. Cytochem. 56 (6), 579-585

Shipping Conditions

Wet Ice

Protein Length

622

NCBI Gene Symbol

MSLN

NCBI GB Accession Number

MSLN

Host or Source

Rabbit

Protein Name

Mesothelin

Nucleotide Accession Number

NM_005823

Peptide Sequence

QKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVL

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