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CD8B Antibody - middle region : FITC (ARP42205_P050-FITC)

Selected Variant

ARP42205_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

CD8b molecule

Gene Aliases

LY3, P37, LEU2, LYT3, CD8B1

Gene ID

926

Swiss Prot

P10966

Accession Number

NP_004922

Host

Rabbit

Reactivity

Human, Rat, Dog, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CD8B

Target

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.

Partner Proteins

ELAVL1; CD8A; CD3D; CD8B; ST3GAL4; LCK

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 79%; Human: 100%; Rabbit: 93%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

21kDa

Shipping Conditions

Wet Ice

Protein Length

210

NCBI Gene Symbol

CD8B

NCBI GB Accession Number

CD8B

Host or Source

Rabbit

Protein Name

T-cell surface glycoprotein CD8 beta chain

Nucleotide Accession Number

NM_004931

Peptide Sequence

KPEDSGIYFCMIVGSPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCR

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