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ATP2A1 Antibody: FITC (ARP42180_P050-FITC)

Product Specifications

Gene Name

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

Gene Aliases

ATP2A, SERCA1

Gene ID

487

Swiss Prot

O14983

Accession Number

NP_004311

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence GTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARV

Target

This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms.

Partner Proteins

UBC; LGR4; WWOX; CFTR; ITPR3; CUL3; PCK1; SLN; IRS2; PLN; IRS1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

110 kDa

Shipping Conditions

Wet Ice

Protein Length

1001

NCBI Gene Symbol

ATP2A1

Protein Name

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Nucleotide Accession Number

NM_004320

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