ATP2A1 Antibody: Biotin (ARP42180_P050-Biotin)
Product Specifications
Gene Name
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Gene Aliases
ATP2A, SERCA1
Gene ID
487
Swiss Prot
O14983
Accession Number
NP_004311
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence GTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARV
Target
This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms.
Partner Proteins
UBC; LGR4; WWOX; CFTR; ITPR3; CUL3; PCK1; SLN; IRS2; PLN; IRS1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
110 kDa
Shipping Conditions
Wet Ice
Protein Length
1001
NCBI Gene Symbol
ATP2A1
Protein Name
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Nucleotide Accession Number
NM_004320
Curated Selection
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