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ACP1 Antibody - N-terminal region : Biotin (ARP42178_T100-Biotin)

Product Specifications

Gene Name

Acid phosphatase 1, soluble

Gene Aliases

HAAP, LMWPTP, LMW-PTP

Gene ID

52

Swiss Prot

P24666

Accession Number

NP_004291

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ACP1

Target

ACP1 belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate.The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

EGFR; US3; VCAM1; ITGA4; FN1; BARD1; RPL12; UBC; COPS5; CDK2; MRPL20; FNBP1L; SFMBT1; EPHB2; EPHB1; FABP4; KDR; SPTAN1; ZAP70; EPHA2; LCK; INSR; FYN; CTNNB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

ACP1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 83%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 92%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Zabell, A.P., (2006) J. Biol. Chem. 281 (10), 6520-6527

Shipping Conditions

Wet Ice

Protein Length

158

NCBI Gene Symbol

ACP1

NCBI GB Accession Number

ACP1

Host or Source

Rabbit

Protein Name

Low molecular weight phosphotyrosine protein phosphatase

Nucleotide Accession Number

NM_004300

Peptide Sequence

PIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIP

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