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MAP3K14 Antibody - N-terminal region : HRP (ARP42161_P050-HRP)

Selected Variant

ARP42161_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Mitogen-activated protein kinase kinase kinase 14

Gene Aliases

HS, NIK, HSNIK, FTDCR1B

Gene ID

9020

Swiss Prot

Q99558

Accession Number

NP_003945

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K14

Target

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Partner Proteins

UBC; TRAF3; TRAF2; BIRC2; TRAF1; IKBKB; HSP90AA1; CHUK; TRAF6; TNAP; PELI3; TRAF5; TANK; NFKB2; ARRB2; ZFP91; EEF1A1; PEBP1; HSP90AB1; CDC37; MAP3K14; EDAR; IKBKAP; RPL6; RPL5; RIPK1; MAP3K7; MAPK3; CASP8; GRB14; GRB10; GRB7; MAP2K4; IKBKG; MAP3K8; RPL4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

104kDa

Shipping Conditions

Wet Ice

Protein Length

947

NCBI Gene Symbol

MAP3K14

NCBI GB Accession Number

MAP3K14

Host or Source

Rabbit

Protein Name

Mitogen-activated protein kinase kinase kinase 14

Nucleotide Accession Number

NM_003954

Peptide Sequence

SEAGPAAISIIAQAECENSQEFSPTFSERIFIAGSKQYSQSESLDQIPNN

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