CES2 Antibody - C-terminal region : Biotin (ARP42158_P050-Biotin)
Product Specifications
Gene Name
Carboxylesterase 2
Gene Aliases
ICE, CE-2, PCE-2, CES2A1
Gene ID
8824
Swiss Prot
O00748
Accession Number
NP_003860
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CES2
Target
Carboxylesterase 2 is a member of a large multigene family. The enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system.Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Sample Type
CES2 is strongly supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/ml
Homology
Dog: 83%; Guinea Pig: 83%; Human: 100%; Mouse: 83%; Rat: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
69kDa
References & Citations
Kimura, K., (2006) Genome Res. 16 (1), 55-65
Shipping Conditions
Wet Ice
Protein Length
623
NCBI Gene Symbol
CES2
NCBI GB Accession Number
CES2
Host or Source
Rabbit
Protein Name
Cocaine esterase
Nucleotide Accession Number
NM_003869
Peptide Sequence
HWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERH
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