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PPFIBP1 Antibody: Biotin (ARP42134_P050-Biotin)

Product Specifications

Gene Name

PTPRF interacting protein, binding protein 1 (liprin beta 1)

Gene Aliases

L2, SGT2, hSGT2, hSgt2p

Gene ID

8496

Swiss Prot

Q86W92

Accession Number

NP_003613

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence QSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRD

Target

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Partner Proteins

VCP; TP53; CDKN1A; CEP76; CEP250; LATS2; YWHAQ; YWHAB; UBC; GRK5; SH3KBP1; ELAVL1; YWHAG; S100A4; PPFIA1; PPFIA3; PPFIA2; PPFIBP1; PTPRM; SFN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

114 kDa

Shipping Conditions

Wet Ice

Protein Length

1011

NCBI Gene Symbol

PPFIBP1

Protein Name

Liprin-beta-1

Nucleotide Accession Number

NM_001198915

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