TNNI1 Antibody - N-terminal region: FITC (ARP42117_P050-FITC)
Product Specifications
Gene Name
Troponin I type 1 (skeletal, slow)
Gene Aliases
TNN1, SSTNI
Gene ID
7135
Swiss Prot
P19237
Accession Number
NP_003272
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TNNI1
Target
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
Partner Proteins
PNMA1; MDFI; TRIM63; TRIM55; TNNC1; TNNT2; EIF3I; CCDC85B; TNNT1; ACTA1; PKD2L1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 93%; Goat: 79%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
21kDa
Shipping Conditions
Wet Ice
Protein Length
187
NCBI Gene Symbol
TNNI1
Protein Name
Troponin I, slow skeletal muscle
Nucleotide Accession Number
NM_003281
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