ALAS2 Antibody - N-terminal region : FITC (ARP41891_T100-FITC)
Selected Variant
ARP41891_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
Aminolevulinate, delta-, synthase 2
Gene Aliases
ASB, ANH1, XLSA, ALASE, XLDPP, XLEPP, ALAS-E, SIDBA1
Gene ID
212
Accession Number
NP_001033058
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS2
Target
ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Partner Proteins
BANP; GRB2; SUCLA2; RABGGTB
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57kDa
References & Citations
Astner, I., (2005) EMBO J. 24 (18), 3166-3177
Shipping Conditions
Wet Ice
Protein Length
515
NCBI Gene Symbol
ALAS2
NCBI GB Accession Number
ALAS2
Host or Source
Rabbit
Nucleotide Accession Number
NM_001037969
Peptide Sequence
VFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQ
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