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TSHR Antibody - C-terminal region : HRP (ARP41871_P050-HRP)

Selected Variant

ARP41871_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Thyroid stimulating hormone receptor

Gene Aliases

LGR3, CHNG1, hTSHR-I

Gene ID

7253

Swiss Prot

Q96GT6

Accession Number

NP_001018046

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TSHR

Target

TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5) .

Partner Proteins

ADRB2; SCRIB; UBC; TSHB; RABAC1; GNA13; GNA12; FLNB; TSHR; GNAQ; PIK3R1; LHCGR; JAK2; JAK1; GNAI3; GNAI2; GNAS; GNA11; GNAO1; GNAI1; HSPA5; FN1; CANX; CALR; STAT3; CALCR

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that TSHR is expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 93%; Sheep: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Claus, M., (2005) Endocrinology 146 (12), 5197-5203

Shipping Conditions

Wet Ice

Protein Length

253

NCBI Gene Symbol

TSHR

NCBI GB Accession Number

TSHR

Host or Source

Rabbit

Protein Name

Thyrotropin receptor

Nucleotide Accession Number

NM_001018036

Peptide Sequence

KLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLLPLGRKSLSFETQKAPRSS

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