TSHR Antibody - C-terminal region : Biotin (ARP41871_P050-Biotin)
Product Specifications
Gene Name
Thyroid stimulating hormone receptor
Gene Aliases
LGR3, CHNG1, hTSHR-I
Gene ID
7253
Swiss Prot
Q96GT6
Accession Number
NP_001018046
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TSHR
Target
TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5) .
Partner Proteins
ADRB2; SCRIB; UBC; TSHB; RABAC1; GNA13; GNA12; FLNB; TSHR; GNAQ; PIK3R1; LHCGR; JAK2; JAK1; GNAI3; GNAI2; GNAS; GNA11; GNAO1; GNAI1; HSPA5; FN1; CANX; CALR; STAT3; CALCR
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
There is BioGPS gene expression data showing that TSHR is expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Cow: 83%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 93%; Sheep: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
References & Citations
Claus, M., (2005) Endocrinology 146 (12), 5197-5203
Shipping Conditions
Wet Ice
Protein Length
253
NCBI Gene Symbol
TSHR
NCBI GB Accession Number
TSHR
Host or Source
Rabbit
Protein Name
Thyrotropin receptor
Nucleotide Accession Number
NM_001018036
Peptide Sequence
KLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLLPLGRKSLSFETQKAPRSS
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