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LSS Antibody - middle region : HRP (ARP41840_P050-HRP)

Product Specifications

Gene Name

Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)

Gene Aliases

OSC, APMR4, HYPT14, CTRCT44

Gene ID

4047

Swiss Prot

P48449

Accession Number

NP_002331

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human LSS

Target

LSS catalyzes the conversion of (S) -2,3 oxidosqualene to lanosterol. It is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene catalyzes the conversion of (S) -2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.

Partner Proteins

UBC; SUMO1; NEDD8; ATP4A; NR4A1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

83kDa

References & Citations

Ma, J., (2007) Atherosclerosis 191 (1), 63-72

Shipping Conditions

Wet Ice

Protein Length

732

NCBI Gene Symbol

LSS

NCBI GB Accession Number

LSS

Host or Source

Rabbit

Protein Name

Lanosterol synthase

Nucleotide Accession Number

NM_002340

Peptide Sequence

KCPHVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSE

Frequently Asked Questions

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