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GHRHR Antibody - N-terminal region : FITC (ARP41816_P050-FITC)

Selected Variant

ARP41816_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Growth hormone releasing hormone receptor

Gene Aliases

GRFR, GHRFR, IGHD4, IGHD1B

Gene ID

2692

Swiss Prot

Q02643

Accession Number

NP_000814

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GHRHR

Target

GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in its gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.This This gene, expressed in the pituitary, encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. Many alternate transcriptional splice variants encoding different isoforms have been described, but only two have been characterized to date.

Partner Proteins

GHRH; GHRL; MLNR

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 85%; Horse: 77%; Human: 100%; Pig: 86%; Rabbit: 79%; Rat: 93%; Sheep: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

References & Citations

Lettre, G., (2007) Hum. Genet. 122 (2), 129-139

Shipping Conditions

Wet Ice

Protein Length

423

NCBI Gene Symbol

GHRHR

NCBI GB Accession Number

GHRHR

Host or Source

Rabbit

Protein Name

Growth hormone-releasing hormone receptor

Nucleotide Accession Number

NM_000823

Peptide Sequence

VTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEE

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