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CYP2A13 Antibody - C-terminal region : FITC (ARP41803_T100-FITC)

Selected Variant

ARP41803_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Cytochrome P450, family 2, subfamily A, polypeptide 13

Gene Aliases

CPAD, CYP2A, CYPIIA13

Gene ID

1553

Swiss Prot

Q16696

Accession Number

NP_000757

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CYP2A13

Target

CYP2A13 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4- (methylnitrosamino) -1- (3-pyridyl) -1-butanone, a major nitrosamine specific to tobacco.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4- (methylnitrosamino) -1- (3-pyridyl) -1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 85%; Rat: 91%; Sheep: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

References & Citations

He, X.Y., (2004) Drug Metab. Dispos. 32 (12), 1516-1521

Shipping Conditions

Wet Ice

Protein Length

494

NCBI Gene Symbol

CYP2A13

NCBI GB Accession Number

CYP2A13

Host or Source

Rabbit

Protein Name

Cytochrome P450 2A13

Nucleotide Accession Number

NM_000766

Peptide Sequence

DPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELF

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