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LOR Antibody - N-terminal region : Biotin (ARP41738_T100-Biotin)

Selected Variant

ARP41738_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Loricrin

Gene Aliases

LOR

Gene ID

4014

Swiss Prot

P23490

Accession Number

NP_000418

Host

Rabbit

Reactivity

Human, Mouse, Cow, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human LOR

Target

LOR is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in LOR may be the cause of both Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.

Partner Proteins

EVPL; VIM; SPRR3; PI3; LOR; KRT1; IVL; CSTA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 93%; Guinea Pig: 75%; Human: 100%; Mouse: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

26kDa

References & Citations

Giardina, E., Ann. Hum. Genet. 68 (PT 6), 639-645 (2004)

Shipping Conditions

Wet Ice

Protein Length

312

NCBI Gene Symbol

LOR

NCBI GB Accession Number

LOR

Host or Source

Rabbit

Protein Name

Loricrin

Nucleotide Accession Number

NM_000427

Peptide Sequence

GYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG

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