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KRT17 Antibody - C-terminal region : Biotin (ARP41733_P050-Biotin)

Product Specifications

Gene Name

Keratin 17

Gene Aliases

PC, K17, PC2, 39.1, CK-17, PCHC1

Gene ID

3872

Swiss Prot

Q04695

Accession Number

NP_000413

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KRT17

Target

KRT17 is type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in its gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.KRT17 encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.

Partner Proteins

TRIM69; UBC; MDM2; IGF2BP3; IKBKG; PA2G4; CRYZ; KDM1A; GRB2; Iqcb1; Nphp1; Invs; CALR; ILF3; UBASH3B; SHC1; PIK3R2; INPPL1; EPS15; CRK; AP2M1; CBL; COPS5; SUMO2; YWHAQ; APC; USP1; UCHL1; CCDC85B; KRT7; KRT6A; EGFR; KRT72; KRT8

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

References & Citations

Rual, J.F., (2005) Nature 437 (7062), 1173-1178

Shipping Conditions

Wet Ice

Protein Length

432

NCBI Gene Symbol

KRT17

NCBI GB Accession Number

KRT17

Host or Source

Rabbit

Protein Name

Keratin, type I cytoskeletal 17

Nucleotide Accession Number

NM_000422

Peptide Sequence

IATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKVISSREQVHQT

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