KRT17 Antibody - C-terminal region : Biotin (ARP41733_P050-Biotin)
Product Specifications
Gene Name
Keratin 17
Gene Aliases
PC, K17, PC2, 39.1, CK-17, PCHC1
Gene ID
3872
Swiss Prot
Q04695
Accession Number
NP_000413
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human KRT17
Target
KRT17 is type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in its gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.KRT17 encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.
Partner Proteins
TRIM69; UBC; MDM2; IGF2BP3; IKBKG; PA2G4; CRYZ; KDM1A; GRB2; Iqcb1; Nphp1; Invs; CALR; ILF3; UBASH3B; SHC1; PIK3R2; INPPL1; EPS15; CRK; AP2M1; CBL; COPS5; SUMO2; YWHAQ; APC; USP1; UCHL1; CCDC85B; KRT7; KRT6A; EGFR; KRT72; KRT8
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
References & Citations
Rual, J.F., (2005) Nature 437 (7062), 1173-1178
Shipping Conditions
Wet Ice
Protein Length
432
NCBI Gene Symbol
KRT17
NCBI GB Accession Number
KRT17
Host or Source
Rabbit
Protein Name
Keratin, type I cytoskeletal 17
Nucleotide Accession Number
NM_000422
Peptide Sequence
IATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKVISSREQVHQT
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