TSHR Antibody - N-terminal region : FITC (ARP41721_P050-FITC)
Product Specifications
Gene Name
Thyroid stimulating hormone receptor
Gene Aliases
LGR3, CHNG1, hTSHR-I
Gene ID
7253
Swiss Prot
P16473
Accession Number
NP_000360
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TSHR
Target
TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5) .
Partner Proteins
ADRB2; SCRIB; UBC; TSHB; RABAC1; GNA13; GNA12; FLNB; TSHR; GNAQ; PIK3R1; LHCGR; JAK2; JAK1; GNAI3; GNAI2; GNAS; GNA11; GNAO1; GNAI1; HSPA5; FN1; CANX; CALR; STAT3; CALCR
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
84kDa
References & Citations
Claus, M., (2005) Endocrinology 146 (12), 5197-5203
Shipping Conditions
Wet Ice
Protein Length
764
NCBI Gene Symbol
TSHR
NCBI GB Accession Number
TSHR
Host or Source
Rabbit
Protein Name
Thyrotropin receptor
Nucleotide Accession Number
NM_000369
Peptide Sequence
ELIARNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLM
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