GAMT Antibody - N-terminal region : Biotin (ARP41685_P050-Biotin)
Selected Variant
ARP41685_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Guanidinoacetate N-methyltransferase
Gene Aliases
PIG2, CCDS2, TP53I2, HEL-S-20
Gene ID
2593
Swiss Prot
Q14353-2
Accession Number
NP_620279
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human GAMT
Target
The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.
Partner Proteins
FOS; CSNK2B; UBC; TERF2IP; POT1; TERF1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
29kDa
Shipping Conditions
Wet Ice
Protein Length
269
NCBI Gene Symbol
GAMT
NCBI GB Accession Number
GAMT
Host or Source
Rabbit
Protein Name
Guanidinoacetate N-methyltransferase
Peptide Sequence
IPLKGLWEDVAPTLPDGHFDGILYDTYPLSEETWHTHQFNFIKNHAFRLL
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