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CYP2D6 Antibody - middle region : Biotin (ARP41676_P050-Biotin)

Product Specifications

Gene Name

Cytochrome P450, family 2, subfamily D, polypeptide 6

Gene Aliases

CPD6, CYP2D, CYP2DL1, CYPIID6, P450C2D, P450DB1, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, P450-DB1

Gene ID

1565

Swiss Prot

Q6NWU0

Accession Number

NP_000097

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CYP2D6

Target

CYP2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to

Partner Proteins

CYP2D6; CYP2C9; POR; CYB5A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CYP2D6 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 92%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Halling, J., (2008) Ther Drug Monit 30 (3), 271-275

Shipping Conditions

Wet Ice

Protein Length

497

NCBI Gene Symbol

CYP2D6

NCBI GB Accession Number

CYP2D6

Host or Source

Rabbit

Protein Name

Cytochrome P450 2D6 EMBL ABB77898.1

Nucleotide Accession Number

NM_000106

Peptide Sequence

EAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV

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