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COMP Antibody - N-terminal region : HRP (ARP41670_P050-HRP)

Selected Variant

ARP41670_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Cartilage oligomeric matrix protein

Gene Aliases

MED, CTS2, EDM1, EPD1, TSP5, PSACH, THBS5

Gene ID

1311

Swiss Prot

P49747

Accession Number

NP_000086

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human COMP

Target

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) .

Partner Proteins

OTX1; FN1; COL9A1; COL2A1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

83kDa

Shipping Conditions

Wet Ice

Protein Length

757

NCBI Gene Symbol

COMP

NCBI GB Accession Number

COMP

Host or Source

Rabbit

Protein Name

Cartilage oligomeric matrix protein

Peptide Sequence

CVLLLTLAALGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQV

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