COMP Antibody - N-terminal region: FITC (ARP41670_P050-FITC)
Product Specifications
Gene Name
Cartilage oligomeric matrix protein
Gene Aliases
MED, CTS2, EDM1, EPD1, TSP5, PSACH, THBS5
Gene ID
1311
Swiss Prot
P49747
Accession Number
NP_000086
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human COMP
Target
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) .
Partner Proteins
OTX1; FN1; COL9A1; COL2A1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
83kDa
Shipping Conditions
Wet Ice
Protein Length
757
NCBI Gene Symbol
COMP
Protein Name
Cartilage oligomeric matrix protein
Curated Selection
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