NOX4 Antibody - middle region: Biotin (ARP41609_P050-Biotin)
Product Specifications
Gene Name
NADPH oxidase 4
Gene Aliases
KOX, KOX-1, RENOX
Gene ID
50507
Swiss Prot
Q9NPH5
Accession Number
NP_001137308.1
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NOX4
Target
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
37kDa
Shipping Conditions
Wet Ice
Protein Length
342
NCBI Gene Symbol
NOX4
Protein Name
NADPH oxidase 4
Nucleotide Accession Number
NM_001143836.2
Curated Selection
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