MARCO Antibody - C-terminal region : Biotin (ARP41581_P050-Biotin)

Product Specifications

Gene Name

Macrophage receptor with collagenous structure

Gene Aliases

SR-A6, SCARA2

Gene ID

8685

Swiss Prot

Q9UEW3

Accession Number

NP_006761

Host

Rabbit

Reactivity

Human, Mouse, Rat, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MARCO

Target

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Partner Proteins

SCGB3A2; SCGB3A1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

MARCO is supported by BioGPS gene expression data to be expressed in COLO205

Concentration

0.5 mg/ml

Homology

Horse: 86%; Human: 100%; Mouse: 85%; Rat: 85%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.