HSD17B6 Antibody - N-terminal region: Biotin (ARP41529_T100-Biotin)
Product Specifications
Gene Name
Hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
Gene Aliases
HSE, RODH, SDR9C6
Gene ID
8630
Swiss Prot
O14756
Accession Number
NP_003716
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human HSD17B6
Target
HSD17B6 has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. HSD17B6 is a member of the retinol dehydrogenase family.The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
HSD17B6 is strongly supported by BioGPS gene expression data to be expressed in A172
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
35kDa
Shipping Conditions
Wet Ice
Protein Length
317
NCBI Gene Symbol
HSD17B6
Protein Name
17-beta-hydroxysteroid dehydrogenase type 6
Nucleotide Accession Number
NM_003725
Curated Selection
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