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HPD Antibody - middle region : Biotin (ARP41493_P050-Biotin)

Product Specifications

Gene Name

4-hydroxyphenylpyruvate dioxygenase

Gene Aliases

PPD, 4HPPD, GLOD3, 4-HPPD, HPPDASE

Gene ID

3242

Swiss Prot

P32754

Accession Number

NP_002141

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HPD

Target

The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria

Partner Proteins

HRSP12; IKBKG; UBC; HIVEP1; CDKN1A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Item, C.B., (2007) Mol. Genet. Metab. 91 (4), 379-383

Shipping Conditions

Wet Ice

Protein Length

393

NCBI Gene Symbol

HPD

NCBI GB Accession Number

HPD

Host or Source

Rabbit

Protein Name

4-hydroxyphenylpyruvate dioxygenase

Nucleotide Accession Number

NM_002150

Peptide Sequence

EMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIV

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