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GPX3 Antibody - N-terminal region : HRP (ARP41491_P050-HRP)

Selected Variant

ARP41491_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Glutathione peroxidase 3 (plasma)

Gene Aliases

GPx-P, GSHPx-3, GSHPx-P

Gene ID

2878

Swiss Prot

P22352

Accession Number

NP_002075

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GPX3

Target

GPX3 belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.

Partner Proteins

UBQLN1; GPX3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

GPX3 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 83%; Guinea Pig: 79%; Human: 100%; Mouse: 100%; Pig: 93%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

References & Citations

Lee, O.J., (2005) Neoplasia 7 (9), 854-861

Shipping Conditions

Wet Ice

Protein Length

226

NCBI Gene Symbol

GPX3

NCBI GB Accession Number

GPX3

Host or Source

Rabbit

Protein Name

Glutathione peroxidase 3

Nucleotide Accession Number

NM_002084

Peptide Sequence

DCHGGISGTIYEYGALTIDGEEYIPFKQYAGKYVLFVNVASYUGLTGQYI

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