GPX3 Antibody - N-terminal region : Biotin (ARP41491_P050-Biotin)
Product Specifications
Gene Name
Glutathione peroxidase 3 (plasma)
Gene Aliases
GPx-P, GSHPx-3, GSHPx-P
Gene ID
2878
Swiss Prot
P22352
Accession Number
NP_002075
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GPX3
Target
GPX3 belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.
Partner Proteins
UBQLN1; GPX3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
GPX3 is strongly supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 83%; Guinea Pig: 79%; Human: 100%; Mouse: 100%; Pig: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
25kDa
References & Citations
Lee, O.J., (2005) Neoplasia 7 (9), 854-861
Shipping Conditions
Wet Ice
Protein Length
226
NCBI Gene Symbol
GPX3
NCBI GB Accession Number
GPX3
Host or Source
Rabbit
Protein Name
Glutathione peroxidase 3
Nucleotide Accession Number
NM_002084
Peptide Sequence
DCHGGISGTIYEYGALTIDGEEYIPFKQYAGKYVLFVNVASYUGLTGQYI
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