DES Antibody - middle region: FITC (ARP41483_P050-FITC)
Product Specifications
Gene Name
Desmin
Gene Aliases
CSM1, CSM2, CDCD3, LGMD1D, LGMD1E, LGMD2R
Gene ID
1674
Swiss Prot
P17661
Accession Number
NP_001918
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DES
Target
DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
PPP1R18; UBE2I; EHHADH; TRIM63; TRIM55; UBC; YWHAQ; MAPKAPK2; CAPN1; MLH1; AURKB; HADHB; MYL6; JUP; HSP90AA5P; HNRNPUL1; CCT7; SNRNP70; RPL29; RPL17; UBD; CRYAB; SHBG; SP1; ITSN1; NEB; PLEKHA5; SYNC; TRIM7; SYNM; ROCK1; PKD1; SPTAN1; S100B; S100A1; DSP
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
53kDa
Shipping Conditions
Wet Ice
Protein Length
470
NCBI Gene Symbol
DES
Protein Name
Desmin
Nucleotide Accession Number
NM_001927
Curated Selection
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