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AGER Antibody - N-terminal region : Biotin (ARP41464_P050-Biotin)

Product Specifications

Gene Name

Advanced glycosylation end product-specific receptor

Gene Aliases

RAGE, sRAGE, SCARJ1

Gene ID

177

Swiss Prot

Q15109

Accession Number

NP_751947

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human AGER

Target

AGER mediates interactions of advanced glycosylation end products (AGE) . These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Galichet, A., (2008) Biochem. Biophys. Res. Commun. 370 (1), 1-5

Shipping Conditions

Wet Ice

Specificity

The immunizing peptide sequence is 100% homologous to all four isoforms of AGER.

Protein Length

342

NCBI Gene Symbol

AGER

NCBI GB Accession Number

AGER

Host or Source

Rabbit

Protein Name

Advanced glycosylation end product-specific receptor

Nucleotide Accession Number

NM_172197

Peptide Sequence

FLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELT

Frequently Asked Questions

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