PON1 Antibody - C-terminal region : Biotin (ARP41401_P050-Biotin)
Product Specifications
Gene Name
Paraoxonase 1
Gene Aliases
ESA, PON, MVCD5
Gene ID
5444
Swiss Prot
P27169
Accession Number
NP_000437
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PON1
Target
PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may mediate an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Partner Proteins
CLU; SUMO4; APOA1; ALB
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 93%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
39kDa
References & Citations
Rosenblat, M., (2006) J. Biol. Chem. 281 (11), 7657-7665
Shipping Conditions
Wet Ice
Protein Length
355
NCBI Gene Symbol
PON1
NCBI GB Accession Number
PON1
Host or Source
Rabbit
Protein Name
Serum paraoxonase/arylesterase 1
Nucleotide Accession Number
NM_000446
Peptide Sequence
ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKA
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