MYBPC3 Antibody - C-terminal region: FITC (ARP41377_P050-FITC)
Product Specifications
Gene Name
Myosin binding protein C, cardiac
Gene Aliases
FHC, CMH4, CMD1MM, LVNC10, MYBP-C, cMyBP-C
Gene ID
4607
Swiss Prot
Q14896
Accession Number
NP_000247.2
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human MYBPC3
Target
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
40kDa
Shipping Conditions
Wet Ice
Protein Length
365
NCBI Gene Symbol
MYBPC3
Protein Name
Myosin-binding protein C, cardiac-type
Nucleotide Accession Number
NM_000256.3
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