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HSD11B2 Antibody - N-terminal region : HRP (ARP41372_P050-HRP)

Product Specifications

Gene Name

Hydroxysteroid (11-beta) dehydrogenase 2

Gene Aliases

AME, AME1, HSD2, HSD11K, SDR9C3

Gene ID

3291

Swiss Prot

P80365

Accession Number

NP_000187

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HSD11B2

Target

HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Partner Proteins

KAT2B; HDAC1; KAT2A; CTBP1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Hovanessian, A.G., (2008) Mol. Cell. Biol. 28 (11), 3830-3849

Shipping Conditions

Wet Ice

Protein Length

44

NCBI Gene Symbol

HSD11B2

NCBI GB Accession Number

HSD11B2

Host or Source

Rabbit

Protein Name

Corticosteroid 11-beta-dehydrogenase isozyme 2

Nucleotide Accession Number

NM_000196

Peptide Sequence

ERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRL

Frequently Asked Questions

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