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FHR4 Antibody - N-terminal region: Biotin (ARP41371_P050-Biotin)

Product Specifications

Gene Name

Complement factor H

Gene Aliases

FHR4, CFHL4, FHR-4

Gene ID

10877

Swiss Prot

Q5DVJ7

Accession Number

NP_006675

Host

Rabbit

Reactivity

Human, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human FHR4

Target

This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs) . This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.

Partner Proteins

CDC42; CFHR4; C3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Human: 100%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

63kDa

Shipping Conditions

Wet Ice

Protein Length

578

NCBI Gene Symbol

CFHR4

Protein Name

Complement factor H-related protein 4A EMBL CAG26679.2

Nucleotide Accession Number

NM_006684

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