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MSH5 Antibody - N-terminal region : Biotin (ARP41356_P050-Biotin)

Product Specifications

Gene Name

MutS homolog 5 (E. coli)

Gene Aliases

G7, NG23, POF13, MUTSH5

Gene ID

4439

Swiss Prot

O43196-2

Accession Number

NP_751897

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MSH5

Target

MSH5 is a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4. This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4. Alternative splicing results in four transcript variants encoding three different isoforms.

Partner Proteins

MSH4; GPS2; UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that MSH5 is expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 86%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

93kDa

References & Citations

Bethke, L., (2008) J. Natl. Cancer Inst. 100 (4), 270-276

Shipping Conditions

Wet Ice

Protein Length

835

NCBI Gene Symbol

MSH5

NCBI GB Accession Number

MSH5

Host or Source

Rabbit

Protein Name

MutS protein homolog 5

Nucleotide Accession Number

NM_172165

Peptide Sequence

DENMTRFLGKLASQEHREPKRPEIIFLPSVDFGLEISKQRLLSGNYSFIP

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