MSH6 Antibody - N-terminal region : FITC (ARP41348_P050-FITC)
Selected Variant
ARP41348_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
MutS homolog 6 (E. coli)
Gene Aliases
GTBP, HSAP, p160, GTMBP, HNPCC5, MMRCS3
Gene ID
2956
Swiss Prot
P52701
Accession Number
NP_000170
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MSH6
Target
This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide bind
Partner Proteins
BRCA1; UBC; SUMO2; PCNA; POLK; SAMHD1; GANAB; HYOU1; SUPT5H; XRCC6; ATP6V1B2; UBD; HDAC11; MSH2; CSNK2A1; SUPT16H; MSH3; MLH1; PMS2; RAD9A; RAD1; MUTYH; HUS1; SLX4; CUL3; NEDD8; FBXO25; SIRT7; XRCC5; PRKDC; BLM; TP53; RAD51; PMS1; SMARCAD1; CHAF1A; DTL; S
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
153kDa
References & Citations
Magnusson, S., (er) Fam. Cancer (2008) In press
Shipping Conditions
Wet Ice
Protein Length
1360
NCBI Gene Symbol
MSH6
NCBI GB Accession Number
MSH6
Host or Source
Rabbit
Protein Name
DNA mismatch repair protein Msh6
Nucleotide Accession Number
NM_000179
Peptide Sequence
ISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
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