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MSH6 Antibody - N-terminal region : Biotin (ARP41348_P050-Biotin)

Product Specifications

Gene Name

MutS homolog 6 (E. coli)

Gene Aliases

GTBP, HSAP, p160, GTMBP, HNPCC5, MMRCS3

Gene ID

2956

Swiss Prot

P52701

Accession Number

NP_000170

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MSH6

Target

This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide bind

Partner Proteins

BRCA1; UBC; SUMO2; PCNA; POLK; SAMHD1; GANAB; HYOU1; SUPT5H; XRCC6; ATP6V1B2; UBD; HDAC11; MSH2; CSNK2A1; SUPT16H; MSH3; MLH1; PMS2; RAD9A; RAD1; MUTYH; HUS1; SLX4; CUL3; NEDD8; FBXO25; SIRT7; XRCC5; PRKDC; BLM; TP53; RAD51; PMS1; SMARCAD1; CHAF1A; DTL; S

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

153kDa

References & Citations

Magnusson, S., (er) Fam. Cancer (2008) In press

Shipping Conditions

Wet Ice

Protein Length

1360

NCBI Gene Symbol

MSH6

NCBI GB Accession Number

MSH6

Host or Source

Rabbit

Protein Name

DNA mismatch repair protein Msh6

Nucleotide Accession Number

NM_000179

Peptide Sequence

ISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR

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