ELAC2 Antibody - C-terminal region: Biotin (ARP41346_P050-Biotin)
Product Specifications
Gene Name
ElaC homolog 2 (E. coli)
Gene Aliases
ELC2, HPC2, COXPD17
Gene ID
60528
Swiss Prot
Q9BQ52-2
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ELAC2
Target
The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC; SUMO2; SUMO1; NEDD8; XPO5; SNX5; ARIH1; TNPO3; WDR4; IPO7; TSN; SARS; PPP2CB; PFDN1; NRD1; HARS; FEN1; FOXH1; SMAD3; SMAD2; COPS5; ASCC2; NDUFA7; GOLM1; CUX1; PUF60
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
ELAC2 is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/mL
Homology
Dog: 100%; Human: 100%; Mouse: 83%; Rat: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
55kDa
Shipping Conditions
Wet Ice
Protein Length
501
NCBI Gene Symbol
ELAC2
Protein Name
Zinc phosphodiesterase ELAC protein 2
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