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ADAM12 Antibody - N-terminal region : HRP (ARP41334_P050-HRP)

Selected Variant

ARP41334_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

ADAM metallopeptidase domain 12

Gene Aliases

MCMP, MLTN, CAR10, MLTNA, MCMPMltna, ADAM12-OT1

Gene ID

8038

Swiss Prot

O43184

Accession Number

NP_067673

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ADAM12

Target

ADAM12 is a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM12 gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.

Partner Proteins

SH3D19; PACSIN3; FSTL3; SRC; PIK3R1; YES1; IGFBP5; IGFBP3; EGF; GRB2; ACTN2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

100kDa

References & Citations

Dyczynska, E., (2008) Int. J. Cancer 122 (11), 2634-2640

Shipping Conditions

Wet Ice

Protein Length

909

NCBI Gene Symbol

ADAM12

NCBI GB Accession Number

ADAM12

Host or Source

Rabbit

Protein Name

Disintegrin and metalloproteinase domain-containing protein 12

Nucleotide Accession Number

NM_021641

Peptide Sequence

VELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVE

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