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WDR12 Antibody - C-terminal region : Biotin (ARP41317_T100-Biotin)

Product Specifications

Gene Name

WD repeat domain 12

Gene Aliases

YTM1

Gene ID

55759

Swiss Prot

Q9GZL7

Accession Number

NP_060726

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human WDR12

Target

WDR12 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The function of this protein is not known.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The function of this protein is not known.

Partner Proteins

UBC; RNF2; BMI1; WDR92; VPS25; ACBD3; VPS29; VPS36; RPUSD2; SNF8; TOM1; TSN; TBCD; SRSF5; PPP3CB; PPP2CB; WDR12; PES1; BOP1; VPS37B; UBE2Z; TBC1D13; SEPHS1; TOMM34; SUGT1; VAT1; USP14; XPO1; TSG101; INPP1; DDX6; GRK5; SIRT7; SUMO2; HIST1H1C; WDR5; NOTCH1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

WDR12 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 89%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

References & Citations

Holzel, M., (2005) J. Cell Biol. 170 (3), 367-378

Shipping Conditions

Wet Ice

Protein Length

423

NCBI Gene Symbol

WDR12

NCBI GB Accession Number

WDR12

Host or Source

Rabbit

Protein Name

Ribosome biogenesis protein WDR12

Nucleotide Accession Number

NM_018256

Peptide Sequence

DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSH

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