THEX1 Antibody - N-terminal region : Biotin (ARP41157_P050-Biotin)
Selected Variant
ARP41157_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Exoribonuclease 1
Gene Aliases
HEXO, THEX1, 3'HEXO
Gene ID
90459
Swiss Prot
Q8IV48
Accession Number
NP_699163
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human THEX1
Target
THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi) .
Partner Proteins
UBC; HNRNPD; HHV8GK18_gp81; SLBP
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 85%; Pig: 93%; Rabbit: 100%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
40kDa
References & Citations
Kupsco, J.M., (2006) RNA 12 (12), 2103-2117
Shipping Conditions
Wet Ice
Protein Length
349
NCBI Gene Symbol
ERI1
NCBI GB Accession Number
ERI1
Host or Source
Rabbit
Protein Name
3'-5' exoribonuclease 1
Nucleotide Accession Number
NM_153332
Peptide Sequence
EPPRPSPEETQQCKFDGQETKGSKFITSSASDFSDPVYKEIAITNGCINR
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